Molecular Mechanism of Constitutive Endocytosis of Acid-Sensing Ion Channel 1a and Its Protective Fu

来源 :The 4th International Ion Channel Conference(第四届国际离子通道会议) | 被引量 : 0次 | 上传用户：zhangsiqin

【摘要】

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【作者】

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Wei-Zheng Zeng Tian-Le Xu

【机构】

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Institute of Medical Science, Shanghai Jiao Tong University School of Medicine

【出处】

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The 4th International Ion Channel Conference(第四届国际离子通道会议)

【发表日期】

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2013年2期

【关键词】

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acid-sensing ion channel trafficking

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Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed in the peripheral and CNSs, which critically contribute to a variety of pathophysiological conditions that involve tissue acidosis, such as ischemic stroke and epileptic seizures.However, the trafficking mechanisms of ASICs and the related proteins remain largely unknown.

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Molecular Mechanism of Constitutive Endocytosis of Acid-Sensing Ion Channel 1a and Its Protective Fu

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