【摘 要】
：
Objective: Human dental pulp stem cells (DPSCs) contain subsets of progenitor/stem cells with high angiogenic,neurogenic and regenerative potential useful for cell therapy.For stem cell therapy, under
【机 构】
：
Department of Oral and Maxillofacial Surgery,School of Dentistry,Aichi-gakuin University;Department
【出 处】
：
11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
Objective: Human dental pulp stem cells (DPSCs) contain subsets of progenitor/stem cells with high angiogenic,neurogenic and regenerative potential useful for cell therapy.For stem cell therapy, understanding the influence of the age of MSCs on their cell properties and regenerative potential is important.In a recent study on human dental pulp stem cells (DPSCs), it has been shown that the supply of autologous pulp tissue and MSC numbers decline with donor age and that aged DPSCs lose their proliferative and migration activities, and differentiation capabilities.We have isolated dental pulp stem cell (DPSC) subsets based on their migratory response to granulocyte-colony stimulating factor (G-CSF)(MDPSCs).Their higher expression of trophic factors, higher trophic effects on migration, immunomodulation and antiapoptosis and regenerative potential have been demonstrated compared to those in DPSCs.Therefore, the objective of this study is to examine the stem cell properties and stabilities of aged MDPSCs in vitro and in vivo compared with young MDPSCs.
其他文献
Objectives: Previous reports based on knock-out mutant mice revealed that Dlx2 mainly regulated the development of tissues from maxillary arch.In this study, we tried to explore the role of Dlx2 over-
Introduction: Cherubism is a rare self-limiting fibro-osseous lesion usually characterized by symmetrical enlargement of the jaws, that with a family history.Cherubism, which was first reported as a f
Objective: Establish database including cases of condyle fracture.Discuss the prognosis in reference to different fracture position, displacement and treatment, Providing reference for the clinic.Meth
Objective: To discuss epidemiological character and relative risk factors ofrnidfacial fractures and to appraise postoperative therapy of midfacial fractures, the report is intended to reveal the risk
The traumatic orbital deformities were divided into ordinary orbital deformities and cranio-facial-orbital deformities.Corresponding surgical treatments were underwent according to the classifications
Objective: To investigate the similarities and differences of human amniotic epithelial cells (hAECs) and bone marrow mesenchymal stem cells (hBMSCs) on the basis of their morphology, proliferation, s
Objective: To investigate the potential risk factors.of oral and maxillofacial surgery staff in posttraumatic stress disorder.Methods: We used PTSD-SS Checklist established by Liu Xianchens to evaluat
Objective: To establish the immortalized oral mucosal epithelial (OME) cell line by transfection with human telomerase reverse transcriptase (hTERT).Methods: Oral mucosal epithelial cells were infecte
Objective: To explore a novel strategy to fabricate tissue engineered cartilage with the shape of human nasal alar by using bone marrow stromal cells (BMSCs) macroaggregate and evaluate the feasibilit
Objectives: The purpose of this study was to evaluate powder type of burn wound dressing materials from silkwarm in animal model.Methods: Total eighteen rats were used in this experiment.Full-thicknes