Over-expression of Dlx2 leads to the post-natal condyle degradation

来源 :11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲 | 被引量 : 0次 | 上传用户：cart008

【摘要】

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【作者】

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Jie-wen Dai Xu-dong Wang Guo-fang Shen

【机构】

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Department of oral craniomaxillofacial science,Shanghai Ninth People's Hospital,Shanghai Jiao Tong

【出处】

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11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲

【发表日期】

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2014年3期

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Objectives: Previous reports based on knock-out mutant mice revealed that Dlx2 mainly regulated the development of tissues from maxillary arch.In this study, we tried to explore the role of Dlx2 over-expression in the post-natal condyle development in mouse.Methods: A transgenic mouse for specifically over-expressing Dlx2 in cranial neural crest cells (CNCCs) was constructed, and the phenotype of post-natal condyle in this mouse was observed using gross observation, micro CT scan and histological examination.

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Over-expression of Dlx2 leads to the post-natal condyle degradation

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