A new method of topical delivery into rat dorsal root ganglion

来源 :The 4th International Ion Channel Conference(第四届国际离子通道会议) | 被引量 : 0次 | 上传用户：lovewebstart

【摘要】

：

【作者】

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Han Hao Yuehui Yang Jinlong Qi Sha Huang Hailin Zhang Nikita Camper Xiaona Du

【机构】

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Department of Pharmacology, Hebei Medical University, Shijiazhuang, PR China

【出处】

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The 4th International Ion Channel Conference(第四届国际离子通道会议)

【发表日期】

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2013年2期

【关键词】

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method topical DRG analgesic

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Dorsal root ganglion (DRG) neurons are the first-order sensory neurons of the spinal somatosensory system.Based on the vital role of DRG neurons in pain signal initiation and transduction, direct manipulation of function of DRG neuron soma body is a valuable way to help understand the pain mechanism.In this study, a new method of targeted delivery of pharmacological agents into DRG was constructed.Briefly, a midline incision was made at the L4-L6 spinal level at rat and the L5 was identified.

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A new method of topical delivery into rat dorsal root ganglion

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