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Objective To compare the advantages and disadvantages of laparoscopic Nissen and Toupet fundoplication in the treatment of hiatal hernia (GERD) and their indications.Methods From 2006 to 2011,263 patients with GERD were randomized into two groups,168 patients undeiwent laparoscopic Nissen fundoplication,and 95 underwent laparoscopic laparoscopic Toupet fundoplication.