【摘 要】
：
Peptidomic studies,i.e.total screening of biological samples for peptides hold considerable promise for elucidating biochemical regulatory networks and for
【机 构】
：
Shemyakin-OvchinnikovInstituteofBioorganicChemistryRussianAcademyofSciencesRussia
【出 处】
：
2008中国深圳蛋白质和多肽科学大会
论文部分内容阅读
Peptidomic studies,i.e.total screening of biological samples for peptides hold considerable promise for elucidating biochemical regulatory networks and for discovery of new bioactive molecules or disease.markers.However,as a relatively young branch of postgenomic research it presents a number of challenges,most of them yet to be resolved.Some of these challenges are listed below:-how far one should (or can) go down the concentration axis in the screening process? -to what extent the extracts of biological samples represent the endogenous composition of peptides? What information can be inferred from the artifacts obtained in course of sample preparation? what are the relative merits and disadvantages of peptidomic studies of different types of biological material (tissues,cell cultures,fluids,etc.)?
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