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  5. JMJD3 NEGATIVELY REGULATES REPROGRAMMING BY PROMOTING INK4A/ARF EXPRESSION AND TARGETING PHF20 FOR U

JMJD3 NEGATIVELY REGULATES REPROGRAMMING BY PROMOTING INK4A/ARF EXPRESSION AND TARGETING PHF20 FOR U

来源 :The 7th Guangzhou International Conference on Stem Cell and | 被引量 : 0次 | 上传用户：bird2000521
【摘 要】
：
Although somatic cell reprogramming can be achieved by several strategies,its efficiency and kinetics of iPSC generation are still very low,suggesting the existence of substantial genetic and epigenet
【作 者】
：
Zhao Wei Li Qingtian Ayers Steven Gu Yifeng Wang Helen Yicheng Wang Rongfu 
【机 构】
：
Houston Methodist Hospital Research Institute
【出 处】
：
The 7th Guangzhou International Conference on Stem Cell and
【发表日期】
：
2014年5期
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Although somatic cell reprogramming can be achieved by several strategies,its efficiency and kinetics of iPSC generation are still very low,suggesting the existence of substantial genetic and epigenetic barriers during reprogramming.Global analysis of euchromatin dynamics during the reprogramming process has revealed orchestrated epigenetic changes at the histone modification level.
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