Identification and functional characterization of lncRNAs in skeletal muscle cells and muscle regene

来源 :The 7th Guangzhou International Conference on Stem Cell and | 被引量 : 0次 | 上传用户:whl98122368
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Emerging studies document the roles of long non-coding RNAs (LncRNAs) in regulating gene expression at chromatin level but relatively less is known how they regulate DNA methylation.Here we identify an lncRNA,Dum in skeletal myoblast cells.The expression of Dum is dynamically regulated during myogenesis in vitro and in vivo.It is also transcriptionally induced by MyoD binding upon myoblast differentiation.
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