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  5. Effects of traditional Chinese medicine brucine on alcohol consumption and preference in alcohol-pre

Effects of traditional Chinese medicine brucine on alcohol consumption and preference in alcohol-pre

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：heyouzhang034
【摘 要】
：
Aim: To evaluate pharmacological and toxicological effects on alcoholism of brucine (BRU), isolated from traditional Chinese medicineStrychnos nux-vo mica.Methods: FH/Wjd rats were used to study the r
【作 者】
：
Yu-ling LI Jian-hui LIANG 
【机 构】
：
National Institute on Drug Dependence, Peking University,Beijing 100191, China
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
brucine alcoholism FH/Wjd rat 
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Aim: To evaluate pharmacological and toxicological effects on alcoholism of brucine (BRU), isolated from traditional Chinese medicineStrychnos nux-vo mica.Methods: FH/Wjd rats were used to study the roles of BRU on alcohol, sucrose intake and their preference in two-bottle choice test.In the paradigm of 5-d alcohol deprivation, antagonism of BRU on alcohol craving was investigated.Besides, the effects of BRU on locomotion, feeding and body weights were measured.
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