【摘 要】
：
Bovine foamy virus (BFV) encodes a transactivator called BTas that enhances viral gene transcription and is essential for BFV replication.BTas contains two major functional domains,the N-terminal DNA-
【机 构】
：
Key Laboratory of Molecular Microbiology and Biotechnology(Ministry of Education)and Key Laboratory
【出 处】
：
第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会
论文部分内容阅读
Bovine foamy virus (BFV) encodes a transactivator called BTas that enhances viral gene transcription and is essential for BFV replication.BTas contains two major functional domains,the N-terminal DNA-binding domain (1-133 aa) and the C-terminal activation domain (198-249 aa),which are necessary for BTas transactivation activity.
其他文献
As Ebola virus outbreak in West Africa continues,the spread of the virus to other regions in the world is a serious concern.Although antibody-based therapy has been shown to be effective in a macaque
The forkhead box O (FOXO) transcription factor family has been shown to play important and diverse roles in many biological processes,such as cell proliferation,cell death,metabolism,and stress respon
SFTSV is an emerging bunyavirus which can cause a severe hemorrhagic fever-like disease with high case fatality rates in humans,posing a serious health threat.However,there are no specific antivirals
Thermostability is a key physical characteristic of virus,and play important roles in vaccine storage and virus transmission.Live attenuated vaccines have been making great contributions to human heal
Coronaviruses possess a cap structure at the 5ends of viral genomic RNA and subgenomic RNAs,which is generated through consecutive methylations by virally encoded guanine-N7-methyltransferase(N7-MTase
Human respiratory syncytial virus(RSV),a negative-strand,non-segmented RNA virus,is the primary cause of viral lower respiratory tract illness in infancy and early childhood worldwide.Despite extensiv
Chicken interleukin-2(chIL-2)and chIL-18 are important lymphokines produced from T lymphocytes or monocyte-macrophages,respectively.Both IL-2 and IL-18 have an important immune-regulatory function for
Phlebovirus,a genus of the Bunyavirus family,causes significant human morbidity and mortality.In response to the host innate immune,phlebovirus NSs protein,which has been identified as an IFN antagoni
Avian paramyxiovirus serotype-1 (APMV-1) can cause acute infectious diseases in birds,and was also known as Newcastle disease virus (NDV).In 2009,we isolated a novel APMV virus from the fecal material
Bovine immunodeficiency virus (BIV) is a kind of lentivirus sharing similar properties in morphology and genetics with human immunodeficiency virus.Here,we replaced the original 5U3 region of BIV infe