【摘 要】
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Objective:The migration inhibition of macrophage is the core event in the development of atherosclerosis.But the mechanisms remain elusive.Oxidized low density lipoprotein (oxLDL) is one of the main f
【机 构】
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Hemorheology Center,Department of Physiology and Pathophysiology,Peking University Health Science Ce
【出 处】
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第十一届全国生物力学学术会议暨第十三届全国生物流变学学术会议
论文部分内容阅读
Objective:The migration inhibition of macrophage is the core event in the development of atherosclerosis.But the mechanisms remain elusive.Oxidized low density lipoprotein (oxLDL) is one of the main factors that in hibit macrophage migration.The cytoskeletal proteins determine the deformability and migration of the cells.Tropomodulin1 (Tmod1) is a cytoskeleton protein that caps the pointed end of actin filaments and plays an important role in cell mechanics.We found that Tmod1 expresses in monocytes and macrophages.
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