Objective: To recognize a novel and optimized combination of epigenetic biomarkers capable of returning higher sensitivity and specificity synergistically in pathologically varied sample groups for ur
Objective: Isolated gonadotropin-releasing hormone(GnRH)deficiency(IGD)is a rare clinical condition with a broad spectrum of human reproductive disorders which varies from congenital isolated hypogona
Objective: Mental health disorders(MHD)in chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)have been widely studied.However,the underlying molecular mechanisms and,in particular,role of inflam
Objective:Mitochondrial damage and oxidative stress play critical roles in the pathogenesis of diabetic nephropathy (DN),especially during renal tubular injury.Our previous study (JASN,2015) has demon
目的 观察雷公藤多甙治疗糖尿病肾病的临床疗效及副作用.方法 56例本院2001年1月-2014年12月住院的糖尿病肾病患者,肝肾功能、血常规正常,24小时尿蛋白定量均在29以上,随机分为治疗组和对照组.治疗组26例,对照组30例,两组均予胰岛素降血糖、血管紧张素转化酶抑制剂(ACEI)或血管紧张素Ⅱ受体阻滞剂(ARB)降压、降尿蛋白,辅以降脂及抗凝治疗,治疗组同时予雷公藤多甙片20mg每天三次,疗
Background: Idiopathic membranous nephropathy(IMN)is a major cause of nephrotic syndrome among adults.Given the special nature course of IMN,when to treat and with which immunosuppressive treatment ne
目的：观察温肾化瘀散结法治疗慢性肾病继发性甲旁亢的临床疗效.方法：将40例患者作为研究对象随机分为对照组和治疗组,对照组给予西药骨化三醇胶丸治疗,治疗组采用温肾化瘀散结法结合骨化三醇胶丸治疗.结果：1.治疗组有效率、iPTH水平降低方面均优于对照组(P＜0.05),2.治疗组在改善骨痛、皮肤瘙痒症状,改善肾小球滤过率、降低钙磷乘积、碱性磷酸酶方面均优于对照组(P＜0.05).结论：温肾化瘀散结法结
目的 探讨局部尿激酶溶栓治疗动静脉内瘘血栓的方法和护理体会,延长内瘘的使用寿命,减少病人的痛苦,提高病人生活质量.方法 我院2013年1月至2013年12月期间,曾发生动静脉内瘘血栓的维持性透析患者9例.其中男性6例,女性3例,年龄45-78岁(平均60±16.2岁).对患者采用下列溶栓治疗,在患者内瘘部位常规消毒后,尿激酶20万单位用生理盐水溶至20ml,选择内瘘血栓的动脉侧距血栓1.5～2.0
Objective:The mechanisms that chondrocytes sense and respond to mechanical stimulation remain largely unknown.HDAC4 has a surprising ability to translocate between the cytoplasm and nucleus.HDAC4 subc
Liposome as a carrier of anti-tumor angiogenesis drug has become one of the frontier research topics in cancer therapies,especially for the targeted liposome-mediated delivery.But many current studies