Interaction of Two Translational Components, Lysyl-tRNA Synthetase and p4037LRP, in Plasma Membrane

来源 :第十五届亚太分子生物学网络组织年会 | 被引量 : 0次 | 上传用户：BCB

【摘要】

：

Although human lysyl-tRNA synthetase (KRS),an enzyme for protein synthesis,is often highly expressed in various cancer cells,its pathophysiological implications

【作者】

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Dae Gyu Kim

【机构】

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MedicinalBioconvergenceResearchCenter,CollegeofPharmacy,SeoulNationalUniversity

【出处】

：

第十五届亚太分子生物学网络组织年会

【发表日期】

：

2012年10期

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Although human lysyl-tRNA synthetase (KRS),an enzyme for protein synthesis,is often highly expressed in various cancer cells,its pathophysiological implications have not been understood.Here we found that KRS induces cancer cell migration through interaction with the 67-kDa laminin receptor (67LR) that is converted from ribosomal subunit p40.

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Interaction of Two Translational Components, Lysyl-tRNA Synthetase and p4037LRP, in Plasma Membrane

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