Graft of NSC-derived neural network restores the disrupted neuronal circuitry after rat spinal cord

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：xiangjin

【摘要】

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【作者】

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Biqin Lai Yuanshan Zeng

【机构】

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Key Laboratory for Stem Cells and Tissue Engineering (Sun Yat-sen University), Ministry of Education

【出处】

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The 18th Congress of the International Federation of Associa

【发表日期】

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2014年8期

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Long-distance regeneration is absent in the adult mammalian CNS, especially when spinal cord is transected completely.We recently reported that a gelatin sponge scaffold with Schwann cells (SCs) overexpressing neurotrophin-3 (NT-3) and neural stem cells (NSCs) overexpressing NT-3 high affinity receptor TrkC could constitute a NSC-derived neural network.

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Graft of NSC-derived neural network restores the disrupted neuronal circuitry after rat spinal cord

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