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Rice blast caused by Magnaporthe oryzae is one of the most destructive diseases of rice worldwide.Like many other foliar pathogens, appressorium differentiation in M.oryzae involves the recognition of various plant surface signals.The cAMP signaling and Pmk1 MAP kinase pathways are known to regulate surface recognition, appressorium formation, and invasive growth.However, the upstream receptors and downstream targets of these two pathways and their relationship are not well characterized.