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本文作者用ELISA检测抗-HCV的方法,调查了肝病患者与其家庭成员的关系,以阐明HCV在家庭内的传播。作者对1980年4月～1989年12月间患慢性非甲非乙型肝炎的107例(男69例,女38例)病人及其296名家庭成员进行调查研究。在107例病例(慢性肝炎43例,肝硬变26例,肝细胞癌38例)中,46例为输血感染者,1例为静脉注射毒品者,其余60例感染途径不明。在296名家庭成员中,双亲21名,配偶75名,子女128名,兄弟姐妹72名,他们的年龄从2岁～78岁,34名<20岁。
The authors used ELISA to measure anti-HCV and investigated the relationship between patients with liver disease and their family members to clarify the spread of HCV in the home. The authors investigated 107 patients (69 males and 38 females) with chronic non-A, non-B hepatitis and their 296 family members from April 1980 to December 1989. Of the 107 cases (43 with chronic hepatitis, 26 with cirrhosis, and 38 with hepatocellular carcinoma), 46 were transfusion-infected, 1 was intravenous, and the remaining 60 were unknown. Among the 296 family members, 21 are parents, 75 are spouses, 128 are children and 72 are brothers and sisters. Their ages range from 2 to 78 years and 34 to 20 years.