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心脏骤停是临床危急症,常规治疗多不奏效.近年,陆续有用大剂量肾上腺素(HDE)复苏成功的报告.但HDE在心肺复苏(CPR)中的合并症及用多大剂量合适仍不清楚.为此,我们对32例心脏骤停病人随机分为两组,分别以常规剂量肾上腺素(SDE)及HDE治疗.报告如下.1 对象和方法本组32例在急诊室或监护病房发生心脏骤停.经心电图或心电监护证实.在胸外心脏按摩、气管插管人工通气等综合治疗基础上,随机分为两组.分别以SDE、HDE治疗.HDE组15例.其中男9例、女6例,年龄18岁～74岁,平均54.3岁.基本病因:脑出血5例.心脏病、肺疾病各3例,DDV中毒2例,糖尿病、药物过敏各1例.心停至注射肾上腺素时间7.1土5.8分钟,肾上腺素用量2～4mg,每3～5分钟1次.平均每例2.1(1～4)次,平均每例总量4.7mg,最多1例16mg.
Cardiac arrest is a clinical emergency and routine treatment is often ineffective. In recent years, successful reports of successful high-dose epinephrine (HDE) resuscitation have been reported. However, it remains unclear whether HDE will be comorbid and adequately used in cardiopulmonary resuscitation (CPR) .Therefore, 32 cases of cardiac arrest patients were randomly divided into two groups, respectively, the conventional dose of epinephrine (SDE) and HDE treatment.Report as follows.1 objects and methods in this group of 32 patients in the emergency room or intensive care unit heart Arrest.Electrocardiogram or ECG monitoring confirmed.In the chest cardiac massage, tracheal intubation and artificial ventilation on the basis of comprehensive treatment, were randomly divided into two groups were treated with SDE, HDE.HDE group of 15 patients.Among them, 9 males , 6 females, aged 18 years old to 74 years old, average 54.3 years old.The basic etiology: cerebral hemorrhage in 5 cases, heart disease, lung disease in 3 cases, DDV poisoning in 2 cases, diabetes mellitus, drug allergy in 1 case. Epinephrine time 7.1 soil 5.8 minutes, epinephrine dosage 2 ~ 4mg, every 3 to 5 minutes 1. The average of 2.1 (1 ~ 4) times each case, the average total amount of 4.7mg per case, up to 1 case of 16mg.