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卵巢颗粒细胞瘤及卵泡膜细胞瘤５０例临床分析山西省肿瘤医院（０３００１３）孟祥兰，邵淑丽，刘尚义卵巢颗粒细胞瘤及卵泡膜细胞瘤均源于卵巢间叶组织或生殖腺基质属于性索间质肿瘤，皆有分泌雌激素的特点。颗粒细胞瘤被认为是低恶性肿瘤，晚期可转移或复发。卵泡膜细胞瘤多属良性。现将我院１９年来手术治疗的５０例分析报告如下。临床资料５０例发病年龄为２６～７６岁，平均５０岁。其中颗粒细胞瘤２２例，平均４７例；混合型颗粒卵泡膜细胞瘤８例，平均４８岁；卵泡膜细胞瘤２０例，平均５５岁。左侧２６例，右侧１５例，双侧９例。绝经前２１例，绝经后２９例。５０例均为已婚妇女，４７例生育史，其中１０例有自然流产史，多达３次；３例原发不孕；１１例继发不孕，大多数未产在３０岁之前。无妊娠与肿瘤同时存在。临床分期：Ⅰ期３５例（其中卵泡膜细胞瘤均为Ⅰ期），Ⅱ期１１例，Ⅲ期和Ⅳ期各２例。临床表现：绝经后子宫出血１１例，个别者发生在绝经后２６年。停经者５例，时间长者１年以上，短者２月，均停经后发生阴道大出血。其中１例闭经一年发现左卵巢肿物，予以单纯肿物切除。术后５年再次出现闭经一年，同时发现右卵巢肿物合并大量腹水，行手术探查右卵巢切除＋全宫＋大网膜及转移灶
Ovarian granulosa cell tumor and theca cell tumor clinical analysis of 50 cases Shanxi Cancer Hospital (030013) Meng Xianglan, Shao Shuli, Liu Shangyi Ovarian granulosa cell tumor and theca cell tumor are derived from ovarian mesenchymal or gonadal stromal tumors are stromal tumors , All have the characteristics of secreting estrogen. Granulocytoma is considered to be a low-grade tumor that can metastasize or recurrent in the advanced stage. Most of theca cells are benign. Now our hospital 19 years of surgical treatment of 50 cases reported as follows. Clinical data of 50 cases of age 26 to 76 years old, average 50 years old. Including granular cell tumor in 22 cases, an average of 47 cases; mixed granular granulosa cell tumor in 8 cases, an average of 48 years; 20 cases of theca cell tumor, with an average of 55 years. Left in 26 cases, right in 15 cases, bilateral in 9 cases. 21 cases before menopause, 29 cases after menopause. 50 cases were married women, 47 cases of reproductive history, of which 10 cases of spontaneous abortion history, up to 3 times; 3 cases of primary infertility; 11 cases of secondary infertility, most were not produced before the age of 30. No pregnancy and tumor co-exist. Clinical stage: stage Ⅰ 35 cases (including the first stage of theca cell tumor), Ⅱ 11 cases, Ⅲ and Ⅳ in 2 cases. Clinical manifestations: 11 cases of postmenopausal uterine bleeding, some individuals in 26 years after menopause. Menopause in 5 cases, the elderly for more than 1 year, the short of February, were vaginal bleeding after menopause. One case of amenorrhea found left ovarian tumor for one year, to be a simple tumor resection. Amenorrhea again after 5 years of a year, at the same time found that the right ovarian mass combined with a large amount of ascites, surgical exploration right ovariectomy + the whole palace + omentum and metastasis