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对35例T2DM患者进行为期两周的胰岛素强化治疗,分析比较治疗前后FPG、(2hPG)、HbA1c、空腹及餐后1、2、3小时C肽分泌。结果胰岛素强化治疗后,FPG、2hPG、HbA1c均较治疗前明显下降(P<0.01);空腹及餐后1、2、3小时C肽均较治疗前明显升高。结论短期胰岛素强化治疗可显著改善T2DM患者C肽的释放。
Thirty-five T2DM patients underwent intensive insulin therapy for two weeks. The levels of FPG, (2hPG), HbA1c before and after treatment, fasting and 1,2,3-hour postprandial C-peptide secretion were analyzed. Results After intensive insulin treatment, the levels of FPG, 2hPG and HbA1c were significantly lower than those before treatment (P <0.01). The fasting and postprandial 1,2,3 and C-peptide levels were significantly higher than those before treatment. Conclusion Short-term intensive insulin therapy can significantly improve the release of C-peptide in T2DM patients.