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[目的]观察丹红注射液联合吗啡治疗Ⅳ期癌症疼痛疗效。[方法]使用随机平行对照方法,将98例住院患者按病志号抽签方法简单随机分两组。对照组48例补液、营养支持、纠正电解质紊乱;吗啡,10mg/次,12h 1次,口服。治疗组50例丹红注射液30mL+0.9%生理盐水250mL,静滴,1次/d;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、疼痛程度分级、疼痛缓解程度、生活质量评价、不良反应。治疗1疗程,判定疗效。[结果]疼痛缓解程度治疗组CR29例,PR16例,MR4例,NC1例,总有效率90.00%;对照组CR18例,PR 20例,MR7例,NC 3例,总有效率79.10%;治疗组优于对照组(P<0.05)。生存质量、KPS评分治疗组优于对照组(P<0.05)。[结论]丹红注射液联合吗啡治疗Ⅳ期癌症疼痛,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Danhong injection combined with morphine on stage Ⅳ cancer pain. [Methods] Using randomized parallel control method, 98 cases of inpatients were randomly divided into two groups randomly according to the method of lot drawing. The control group, 48 cases of fluid replacement, nutritional support, correct electrolyte imbalance; morphine, 10mg / time, 12h 1 times, orally. Treatment group, 50 cases of Danhong injection 30mL + 0.9% saline 250mL, intravenous infusion, 1 / d; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Clinical symptoms, grading of pain, degree of pain relief, quality of life, and adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Results] The degree of pain relief in the treatment group CR29, PR16, MR4, NC1 cases, the total effective rate 90.00%; control group CR18, PR20, MR7, NC 3 cases, the total effective rate was 79.10% Better than the control group (P <0.05). Quality of life, KPS score treatment group than the control group (P <0.05). [Conclusion] Danhong injection combined with morphine can treat stage Ⅳ cancer pain with satisfactory curative effect and no serious adverse reactions, which deserves promotion.