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目的:探讨原发性高血压患者血清C反应蛋白(CRP)、尿酸(UA)及室间隔厚度(IVST)测量值与高血压发病的相关性。方法:对行冠脉造影的161例患者根据有无合并高血压分为高血压组98例和非高血压组63例。均测量血清CRP、UA、空腹血糖(FBG)、肝肾功能。结果:高血压组血清CRP和IVST显著高于非高血压组(P<0.05);冠状动脉造影阳性患者中,高血压患者CRP和IVST显著高于非高血压患者(P<0.05);冠状动脉造影阴性患者中,高血压患者CRP、UA和IVST显著高于非高血压患者(P<0.05)。结论:CRP和IVST与高血压发病呈显著相关性。
Objective: To investigate the correlation between serum C-reactive protein (CRP), uric acid (UA) and interventricular septal thickness (IVST) and the incidence of hypertension in patients with essential hypertension. Methods: 161 patients undergoing coronary angiography were divided into hypertension group (n = 98) and non-hypertension group (n = 63) according to the presence or absence of hypertension. Serum CRP, UA, fasting blood glucose (FBG), liver and kidney function were measured. Results: The serum levels of CRP and IVST in hypertension group were significantly higher than those in non-hypertension group (P <0.05). CRP and IVST were significantly higher in patients with coronary artery disease than in non-hypertension group (P <0.05) CRP, UA and IVST were significantly higher in hypertensive patients than in non-hypertensive patients (P <0.05). Conclusion: There is a significant correlation between CRP and IVST and the incidence of hypertension.