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目的:研究代谢综合征虚、实证型患者血管内皮功能变化情况。方法:以本院124例代谢综合征(MS)患者为研究对象,按中医辨证分为虚证组53例,实证组71例,以60例正常人为对照组,测定血浆内皮素(ET)、一氧化氮合酶(NOS)的水平。结果:3组之间的ET水平存在显著差异:实证组与健康对照组、虚证组与健康对照组比较有非常显著差异(P<0.01),且实证组与虚证组比较亦有显著差异(P<0.05);3组之间的NOS水平存在显著差异:实证组与健康对照组、虚证组与健康对照组比较有显著差异(P<0.05),且实证组与虚证组比较亦有显著差异(P<0.05)。结论:MS患者虚实证型的区别同时体现在收缩血管作用增强、舒张血管作用减弱两对立方面。
Objective: To study the changes of vascular endothelial function in patients with metabolic syndrome deficiency and positive type. Methods: A total of 124 patients with metabolic syndrome (MS) in our hospital were divided into three groups: asthenia syndrome group (53 cases), empirical group (71 cases) and normal control group (60 cases) Nitric oxide synthase (NOS) levels. Results: There were significant differences in ET levels among the three groups: there was a significant difference (P <0.01) between the experimental group and the healthy control group and between the deficiency syndrome group and the healthy control group, and there was a significant difference between the experimental group and the deficiency syndrome group (P <0.05). The levels of NOS in the three groups were significantly different between the experimental group and the healthy control group, the deficiency syndrome group and the healthy control group (P <0.05), and the difference between the experimental group and the deficiency syndrome group There was a significant difference (P <0.05). Conclusion: The difference between the syndromes of deficiency and deficiency of MS patients is manifested in the two contradictory aspects of enhancement of vasoconstriction and relaxation of vasodilatation.