稳定型心绞痛时卡托普利对二硝酸异山梨醇酯的增强作用

来源 :国外医学.心血管疾病分册 | 被引量 : 0次 | 上传用户:myqwe
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此文报告血管紧张素转换酶抑制剂卡托普利对单独口服二硝酸异山梨醇酯(ISDN)的冠心病人有增加其药效的作用。研究对象为14例男性冠状动脉疾病伴有稳定型心绞痛的病人,年龄45~62岁,平均53岁。按加拿大心血管学会的功能分级,其中6人属2级,8人属3级,6人在6个月前或更久有心肌梗塞,12例作冠状动脉造影证实至少有1支主要冠状动脉腔内直径的狭窄大于75%。全部病人运动试验阳性,具有典型的心绞痛症状和 ST段水平下降或斜行下降大于 1mm。休息时有心绞痛、合并高血压充血性心衰及 This article reports the role of the angiotensin converting enzyme inhibitor captopril in increasing coronary artery disease in patients with isosorbide dinitrate (ISDN) alone. Study of 14 patients with coronary artery disease with stable angina patients, aged 45 to 62 years, mean 53 years. According to the functional classification of the Canadian Cardiovascular Society, 6 were in grade 2, 8 were in grade 3, 6 had myocardial infarction 6 months or longer, and 12 had coronary angiography confirmed at least one major coronary artery The diameter of the lumen is greater than 75%. All patients had a positive motor test with typical symptoms of angina and decreased ST-segment levels or a ramp-down greater than 1 mm. Rest angina pectoris, congestive heart failure and hypertension
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