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通过稳定微小气泡试验(SMT),对足月和接近足月的伴有呼吸窘迫的婴儿进行了表面活性物质功能研究, 本次研究临床初步诊断为短暂呼吸急促(TTN)需要供氧和监控的,胎龄≥34周的新生儿。为了进行SMT,在分娩后马上收集胃内吸出液。第1部胸部X线片分别由3位影像科医生独立进行检查,根据他们的解释,婴儿可分为3个组:1组是TTN组,2组是新生儿呼吸窘迫综合征(RDS)组,3组是X线片界线难以界定组。对32 例呼吸窘迫的婴儿与一组胎龄及出生体重相同的对照组婴儿进行了研究。与对照组相比,呼吸窘迫组的稳定微小气泡(SMB)计数的中位数以及四分值范围(IOR)都小得多(P<0.001),呼吸窘迫组的稳定微小气泡计数的中位数为17,极差6-33;而对照组的稳定微小气泡计数的中位数为120,极差79-275。在每平方毫米小于35个稳定微小气泡计数(SMB/mm2)的婴儿的比例是大大不同的。呼吸窘迫组中比例为75%(24/32),TTN组为69%(9/13),RDS为100%(5/5),界定模糊组为83%(10/12),而对照组中比例为6%(2/32,P< 0.05)。92%(24/26)的婴儿需要大于24 h的供氧,而那些需要供氧小于24 h的婴儿中只有17%(1/6)的气泡计数小于35 SMB/mm2(P<0.05)。结论:结果表明在患有BDS的病例中,大多数接近足月和可能足月的婴
Surfactant functional studies were performed on full-term and near-term infants with respiratory distress through stable micro-bubble tests (SMT). The initial clinical diagnosis of transient thirst (TTN) in this study required oxygenation and monitoring , Neonatal gestational age ≥34 weeks. For SMT, gastric aspirate is collected immediately after delivery. According to their interpretation, infants can be divided into three groups: one is the TTN group and the other two is the neonatal respiratory distress syndrome (RDS) group , 3 groups is difficult to define the boundaries of X-ray group. Thirty-two infants with respiratory distress were studied with a group of infants of the same gestational age and birth weight. The median number of stable micro-bubble (SMB) counts and the quartile range (IOR) for respiratory distress patients were much smaller (P <0.001) compared with controls, and the median number of stable microvessel counts for respiratory distress patients The number of 17, very poor 6-33; and the control group of stable micro-bubble count median of 120, very poor 79-275. The proportion of infants less than 35 stable microbubbles per square millimeter (SMB / mm2) is significantly different. Respiratory distress was 75% (24/32) in the TTN group, 69% (9/13) in the TTN group, 100% (5/5) in the RDS group and 83% (10/12) in the defocused group, whereas the control group In the ratio of 6% (2/32, P <0.05). 92% (24/26) of infants required more than 24 hours of oxygen supply, while only 17% (1/6) of those infants who required less than 24 hours of oxygen were less than 35 SMB / mm2 (P <0.05). Conclusions: The results show that in the cases with BDS most of the infants approaching full-term and possibly full-term infants