论文部分内容阅读
目的调查不同乙肝病毒感染状态的孕妇经被动免疫后所生婴儿乙肝病毒感染情况。方法选取某院2009年11月～2012年3月114例乙肝孕妇为研究对象,随机分成被动免疫组(52例孕妇)和未被动免疫组(62例孕妇),针对其生育婴儿的相关情况进行比较分析。结果 (1)两组婴儿出生后抗HBs抗体产生率方面比较,被动免疫组高于未被动免疫组,差异有统计学意义(P﹤0.05);两组婴儿在乙肝病毒感染率方面比较,被动免疫组低于未被动免疫组,差异有统计学意义(P﹤0.05)。(2)乙肝“大三阳”孕妇两组婴儿在出生后抗HBs抗体产生率方面比较,被动免疫组高于未被动免疫组,差异有统计学意义(P﹤0.05);两组婴儿在乙肝病毒感染率方面比较,被动免疫组低于未被动免疫组,差异有统计学意义(P﹤0.05)。结论被动免疫在阻断乙肝孕妇宫内感染率方面的临床效果较好。
Objective To investigate the status of hepatitis B virus infection in pregnant women with different status of hepatitis B virus infection after passive immunization. Methods A total of 114 pregnant women with hepatitis B from November 2009 to March 2012 in our hospital were selected and randomly divided into passive immunization group (52 pregnant women) and passive immunization group (62 pregnant women), according to their relatives comparative analysis. Results (1) The incidence of anti-HBs antibody in infants after birth was significantly higher in passive immunization group than in passive immunization group (P <0.05). The incidence of hepatitis B virus infection in both groups was significantly lower than that in passive immunization group Immunization group was lower than the passive immunization group, the difference was statistically significant (P <0.05). (2) Compared with non-passive immunization group, the passive immunization group had significant difference (P <0.05) in the incidence of anti-HBs antibody after birth between two groups of infants with hepatitis B and “big three positive” In the aspect of hepatitis B virus infection rate, the passive immunization group was lower than the non-passive immunization group, the difference was statistically significant (P <0.05). Conclusion Passive immunization has a good clinical effect in blocking the intrauterine infection rate of pregnant women with HBV.