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作者前瞻性观察了199例住院的不稳定型心绞痛病人,其中男156,女43例,平均年龄62岁。除常规临床、心电图和酶学检查外,还连续测定总肌酸激酶(CK),以评价它的预后价值,平均随访13.6个月。病人入院后最初18小时每4小时测定 CK1次,以后30小时内至少每12小时测定1次。结果根据有无一过性心电图 ST-T 变化和血清 CK 增加将病人分为4组;A 组心电图和酶均无变化;B 组无心电图变化但血清酶升高;C 组有心电图变化但无酶变化;D 组心电图和酶均有变化。其中急性冠状动脉机能不全占77%,进展型心绞痛占23%,两种不稳定型心绞痛在4组中的分布大致相等。
The prospective observation of 199 cases of hospitalized patients with unstable angina, including 156 males and 43 females, mean age 62 years. In addition to routine clinical, electrocardiographic and enzymatic tests, total creatine kinase (CK) was also continuously measured to assess its prognostic value with an average follow-up of 13.6 months. The patient was tested for CK1 every 4 hours for the first 18 hours after admission and at least once every 12 hours for 30 hours thereafter. Results The patients were divided into 4 groups according to the changes of ST-T and serum CK. The changes of ECG and enzyme in group A were not observed. The changes of ECG were not observed in group B but the changes of ECG were observed in group C. However, Enzyme changes; D group ECG and enzyme changes. Among them, acute coronary insufficiency accounted for 77%, advanced angina pectoris 23%, two unstable angina pectoris in the four groups were roughly equal.