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目的:探讨复方中药对 L_(1210)白血病小鼠抗肿瘤机理。方法:采用益气养阴和补气养血方中药观察其对 L_(1210)白血病小鼠在体天然杀伤细胞(NK 细胞)活性,采用体外培养观察这两方中药对 L_(1210)白血病细胞增殖抑制作用。结果:两方中药均可增加荷瘤小鼠的 NK细胞活性(P<0.01和 P<0.05),补气养血方中药还有抑制培养 L_(1210)白血病细胞的直接作用(P<0.05)。结论:两方中药通过增强机体 NK 细胞活性,补气养血中药还可通过抑瘤生长发挥治疗作用。
Objective: To investigate the anti-tumor mechanism of compound Chinese herbs on L_(1210) leukemia mice. METHODS: The NK cell activity of L_(1210) leukemia mice was observed by traditional Chinese medicine for supplementing qi and nourishing yin and supplementing qi and nourishing blood. The in vitro culture was used to observe the effects of the two herbs on L_(1210) leukemia cells. Inhibition of proliferation. Results: Both herbs could increase the activity of NK cells in tumor-bearing mice (P<0.01 and P<0.05). Buqiyangxue Recipe also had the direct effect of inhibiting the growth of L_(1210) leukemia cells (P<0.05). . Conclusion: Both traditional Chinese medicines can increase the activity of NK cells, and qi and blood-nourishing herbs can also play a therapeutic role through tumor growth inhibition.