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目的探讨玻璃体视网膜手术方式及各种眼内填充物对角膜内皮的影响。方法对１２９例患者（１３６只眼），其中糖尿病患者４８人（５４只眼），行单纯玻璃体切割术、玻璃体切割硅油填充术及玻璃体切割六氟化硫（ＳＦ６）注入术，测定了术前、术后２、４、８周、３月及６月的角膜内皮细胞密度。结果在眼压控制良好的情况下，有晶状体眼行玻璃体视网膜手术的手术方式、眼内填充物的选择及糖尿病对角膜内皮细胞密度均无显著影响。结论在眼压控制良好的情况下，无论是糖尿病还是非糖尿病患者有晶状体眼行玻璃体视网膜手术对角膜内皮是较为安全的
Objective To investigate the effect of vitreoretinal surgery and various intraocular fillings on the corneal endothelium. Methods A total of 129 patients (136 eyes), 48 (54 eyes) with diabetes mellitus, underwent simple vitrectomy, vitrectomy silicone oil filling and vitrectomy with SF6. , 2, 4, 8 weeks postoperatively, 3 months and 6 months corneal endothelial cell density. Results Under the condition of good intraocular pressure control, there was no significant effect of vitreoretinal surgery, intraocular filling and diabetes on corneal endothelial cell density. Conclusions In patients with well-controlled intraocular pressure, vitreoretinal surgery in patients with diabetes mellitus and in non-diabetic patients is safer for corneal endothelium