论文部分内容阅读
人类及多数哺乳动物卵巢内卵泡数目,随年龄增长不断减少。卵泡的最大“损耗”发生在出生以前,人类在胎儿第5个月时卵泡高达七百万个,到足月分娩时就只剩二百万了。妇女一生中,只有少数卵泡能够发育成熟、排卵。其余大部分在发育不同阶段经闭锁(atresia)退化而消失。卵泡闭锁,在形态上可出现一系列的变化。Ro-bert 认为,卵细胞染色体密集和溶解、核皱缩以及卵泡表面颗粒细胞出现核固缩、颗粒细胞从粒膜层脱落浮于卵泡液中,甚至整个细胞破碎,为最可信及最敏感的形态上的变化。在卵泡闭锁过程中,也伴随某些组织化学性能的变化。例如:胸腺嘧啶核苷
The number of follicles in human and most mammalian ovaries decreases with age. The largest “loss” of follicles occurred before birth, when humans had as many as seven million follicles at the fifth month of life and only two million at term. Women’s life, only a few follicles to mature, ovulation. Most of the rest disappears by atresia degeneration at different stages of development. Follicles atresia, in the form of a series of changes can occur. Ro-bert believes that the egg cells dense and dissolved chromosomes, nuclear shrinkage and granulosa cells on the surface of the nucleus shrinkage, granulosa cells from the granulosa layer floating in the follicular fluid, and even the entire cell fragmentation, the most credible and most sensitive Morphological changes. In the process of follicular atresia, but also accompanied by changes in the chemical properties of certain tissues. For example: thymidine