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在田鼠石棉肺病程中,肺泡上皮细胞由于石棉纤维的不断刺激常失去其Ⅰ型或Ⅱ型细胞结构(Ⅰ型有薄层细胞浆构成气体交换屏障,Ⅱ型细胞有嗜锇层状物),并转变为上皮细胞与肺泡巨噬细胞的中间型。本文作者报告上述变化过程的实验结果。
Alveolar epithelial cells often lose their type I or type II cellular structure (type I thin lamina cytoplasm constitutes gas exchange barrier, type II cells osmiophilic laminar layer) in asbestos lung field. And transformed into epithelial cells and alveolar macrophages in the middle. The authors report the experimental results of the above change process.