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地高辛——利尿剂所致的心脏病是一个常见的严重的药理性心脏病,它是由不适当使用地高辛与排钾性利尿剂所致。文献曾指出,对于适量应用地高辛的患者一般不可能产生一个持续平稳的洋地黄化状态,当应用不适剂量时,其中毒的情况很可能发生。近来提出注意是,在经常使用排钾性利尿剂导致钾负平衡的状态下而应用了不适量地高辛,这就增加了患者对洋地黄的
Digoxin - Diuretic-induced heart disease is a common and serious pharmacological heart disease caused by inappropriate use of digoxin and potassium-releasing diuretics. It has been pointed out in the literature that it is not generally possible for patients with moderate doses of digoxin to produce a sustained, steady state of digitalis, which is most likely to occur when unsuitable doses are applied. It has recently been noted that the inappropriate use of digoxin in the state in which potassium-releasing diuretics often lead to negative potassium balance increases the patient’s response to digitalis