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粗制棉籽油可以引起不育症。1971年被证实其有效成分为棉酚。学者们对其抗生育机制提出过种种推测,其中包括棉酚影响睾酮的分泌、抑制精子细胞的分化破坏血睾屏障、促进前列腺素生物合成和直接作用于成熟精子,特别是降低人精子活力及其对果糖的作用。根据棉酚的抗生育作用,有人提出棉酚作为廉价阴道杀精剂的设想,而且认为其副作用肯定会比许多沿用的避孕措施小。目前棉酚
Crude cottonseed oil can cause infertility. 1971 proved to be the active ingredient of gossypol. Scholars have put forward various speculations about their anti-fertility mechanisms, including gossypol affecting the secretion of testosterone, inhibiting the differentiation of sperm cells and damaging the blood-testis barrier, promoting prostaglandin biosynthesis and directly acting on mature sperm, especially reducing human sperm motility and Its effect on fructose. According to the anti-fertility effect of gossypol, the idea of gossypol as a cheap vaginal spermicide has been proposed and its side effects are sure to be smaller than many of the contraceptive methods used. Currently gossypol