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本文作者曾报道不发展为艾滋病的人类免疫缺陷症病毒(HIV)感染者(NP)体内存在抗β2微球蛋白衍生肽R7V抗体。为研究R7V基元可否作为中和作用的潜在靶位,作者从NP者和R7V免疫的家兔血清中纯化出抗R7V抗体,并将抗-R7V与不同亚型HIV-1分离株和
The authors have reported the presence of anti-β2 microglobulin-derived peptide R7V antibodies in human immunodeficiency virus (HIV) infected individuals (NPs) who do not develop AIDS. To investigate whether R7V motifs may serve as potential targets for neutralization, the authors purified anti-R7V antibodies from rabbits immunized with NP and R7V and compared anti-R7V with different subtype HIV-1 isolates and