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多囊卵巢综合征(PCOS)主要累及生育年龄妇女,可引起内分泌和代谢紊乱。其临床表现复杂多样,患者常伴有肥胖、外周组织胰岛素抵抗和胰岛素细胞功能缺陷,增加其糖耐量异常和患糖尿病的概率。此外,PCOS还常伴有血脂异常和高血压等代谢障碍。这些都可能增加PCOS患者的妊娠期并发症如妊娠期糖尿病及妊娠期高血压的风险。综述PCOS对妊娠期并发症及新生儿结局的影响。
Polycystic ovary syndrome (PCOS) mainly affects women of childbearing age, can cause endocrine and metabolic disorders. Its complex and diverse clinical manifestations, patients are often accompanied by obesity, peripheral tissue insulin resistance and insulin cell dysfunction, increase their probability of impaired glucose tolerance and diabetes. In addition, PCOS often accompanied by dyslipidemia and hypertension and other metabolic disorders. All of these may increase the risk of gestational complications such as gestational diabetes and gestational hypertension in PCOS patients. The effects of PCOS on gestational complications and neonatal outcomes were reviewed.