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16例药物或手术治疗失败的子宫内膜异位症患者,其中14例为绝经前,均接受芳香酶抑制剂来曲唑治疗(2.5mg/d),并加用促性腺激素抑制剂炔诺酮醋酸或复方口服避孕药,治疗时间平均6个月。结果疼痛得分中位数从开始治疗时的7下降为治疗结束时的1.5。但芳香酶抑制剂可引起骨质疏松症(应与二膦酸盐联合用药)、轻度潮热和性欲减退。因此,对于现有治疗不应答或者因副作用不能使用现
Sixteen patients with endometriosis who had failed medical or surgical treatment, of whom 14 were premenopausal, received both the aromatase inhibitor letrozole (2.5 mg / d) and gonadotropin-inhibitor norethindrone Keto acetic acid or compound oral contraceptives, the average treatment time of 6 months. Results The median pain score decreased from 7 at the start of treatment to 1.5 at the end of treatment. However, aromatase inhibitors can cause osteoporosis (should be combined with bisphosphonates), mild hot flashes and loss of libido. Therefore, do not respond to existing treatment or because of side effects can not be used now