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为了观察转铁蛋白受体单抗偶联物对晚期肺癌的疗效，采用转铁蛋白受体单克隆抗体与表阿霉素、顺铂等化学药物制成偶联物，对３８例中晚期肺癌进行选择性支气管动脉插管灌注，结果：ＣＲ１２例，占３１．６％，ＰＲ１７例，占４４．７％，ＮＣ７例，占１８．４％，ＰＤ２例，占５．３％，总有效率（ＣＲ＋ＰＲ）为７６．３％。通过病例观察，支气管动脉插管导向灌注疗法比单纯化疗药物动脉灌注的疗效为优，且副作用小，为中晚期肺癌的姑息治疗提供了新的有效方法
In order to observe the efficacy of transferrin receptor monoclonal antibody conjugates for advanced lung cancer, conjugates using transferrin receptor monoclonal antibodies and epirubicin, cisplatin and other chemical drugs were used to treat 38 patients with advanced lung cancer. Selective bronchial arterial intubation was performed. Results: CR12 cases (31.6%), PR17 cases (44.7%), NC7 cases (18.4%), PD2 cases (5.3%), total effective rate (CR+PR) is 76.3%. Through case observation, bronchial arterial catheter-guided infusion therapy is superior to arterial perfusion with chemotherapy alone, and has fewer side effects, providing a new and effective method for the palliative treatment of lung cancer in middle and late stage.