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目的:探讨建和汤联合灌肠治疗对Ⅰ～Ⅲ期慢性肾功能衰竭及微炎症状态的影响.方法:选择在我院就诊的60例Ⅰ～Ⅲ慢性肾衰患者,利用随机数值法分为治疗组及对照组,每组患者30例.对照组给予常规的西药治疗,治疗组在常规的西药治疗的基础上,加用建和汤灌肠治疗.对比两组治疗前后两组病例的中医症候疗效和肾功能指标以及微炎症状态指标,即:内生肌酐清除率(Ccr)、血尿素氮(BUN)、超敏C反应蛋白(hs-CRP)、血肌酐(Scr);分析两组试验的有效率.结果:治疗组疗效有效率90.0％,明显高于对照组73.3％,差异具有统计学意义(P＜0.05);治疗后治疗组症候状态有效率优于对照组(P＜0.01);治疗组在治疗后肾功能指标和微炎症指标明显优于对照组,差异具有统计学意义(P＜0.05).结论:建和汤联合灌肠治疗对Ⅰ～Ⅲ期慢性肾功能衰竭及微炎症状态患者具有显著的疗效.“,”Objective:To explore the effect of the Jianhe Decoction combined with enema on micro inflammatory state in the treatment of patients with Ⅰ ～ Ⅲ phase chronic renal failure.Methods:60 cases of chronic renal failure patients in our hospital were randomly divided into experimental group and controlled group,30 cases of each group.Given the controlled group conventional western medicine treatment,the experimental group plus Jianhe Decoction and enema treatment.Compared TCM syndrome and renal function index and micro inflammatory state index of the two groups before and after treatment,such as:endogenous creatinine clearance rate (Ccr),blood urea nitrogen (BUN),high sensitive C reactive protein (hs-CRP),serum creatinine (Scr),and analzed the efficiency of the two groups.Results:The effective rate of the treatment group (90％) was significantly higher than the controlled group (73.3％),the difference was statistically significant (P ＜ 0.05).After treatment,the effective rate of the treatment group was better than the controlled group (P ＜ 0.01).The renal function and micro inflammation index of the experimental group were significantly better than those of the controlled group,the difference was statistically significant (P ＜ 0.05).Conclusion:The effect of Jianhe Decoction combined with enema on the micro inflammatory state in the treatment of patients with Ⅰ ～ Ⅲ phase chronic renal failure is significant.