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目的:观察清热祛湿法联合西药治疗溃疡性结肠炎的效果。方法:选择2012年7月~2014年7月于本院收治的溃疡性结肠炎患者150例,随机分为观察组和对照组各75例,分别给予清热祛湿联合西药治疗与常规西药治疗,比较两组治疗后效果,并对主要症状改善情况、不良反应发生情况、中医证候积分情况及复发率等进行观察。结果:1经治疗后观察组总有效率98.67%,对照组总有效率84%,两组比较差异有统计学意义(P<0.05)。2观察组经治疗后腹痛、腹泻、黏液血便及里急后重等主要临床症状改善情况相比对照组差异有统计学意义(P<0.05);观察组患者在治疗过程中均未有不良反应发生,耐受性均较好,对照组患者有1例发生恶心、呕吐,持续2天后症状消失。3经治疗后两组中医证候积分组内比较,在治疗2周、4周及3个月时两两比较差异有统计学意义(P<0.05),组间比较观察组积分改善更为明显,尤其于治疗4周,治疗3个月观察组疗效相比对照组差异有统计学意义(P<0.05),治疗6个月随访结果表明观察组疗效稳定,而对照组积分升高。4随访6个月,对经治疗治愈和有效的患者(观察组74例,对照组63例)进行复发情况调查,结果为观察组复发10例,复发率13.51%,对照组复发33例,复发率52.38%,两组比较差异有统计学意义(P<0.05)。结论:采用清热祛湿法联合西药治疗溃疡性结肠炎效果较好,疗效稳定持久,值得在临床上推广应用。
Objective: To observe the effect of heat dampness combined with western medicine in the treatment of ulcerative colitis. Methods: A total of 150 patients with ulcerative colitis admitted to our hospital from July 2012 to July 2014 were randomly divided into observation group (75 cases) and control group (75 cases) The effects of the two groups after treatment were compared, and the improvement of the main symptoms, the occurrence of adverse reactions, the TCM syndrome score and the relapse rate were observed. Results: 1 After treatment, the total effective rate was 98.67% in the observation group and 84% in the control group. The difference between the two groups was statistically significant (P <0.05). (2) There was significant difference in the improvement of the main clinical symptoms such as abdominal pain, diarrhea, mucous bloody stool and tenesmus in the observation group compared with the control group (P <0.05). No adverse reaction occurred in the observation group during the treatment, Affected better, 1 patient in the control group nausea, vomiting, symptoms disappeared after 2 days. 3 After treatment, the scores of TCM syndromes in the two groups were statistically significant (P <0.05) at 2 weeks, 4 weeks and 3 months after treatment, and the scores of the observation group improved more obviously , Especially in the treatment of 4 weeks, 3 months of treatment group compared with the control group, the difference was statistically significant (P <0.05), the treatment of 6 months follow-up results showed that the observation group, the efficacy of stable, while the control group increased. 4 Follow-up 6 months, the cured and effective treatment of patients (observation group of 74 cases, 63 cases of control group) recurrence survey, the results of the observation group of 10 patients relapsed, the recurrence rate was 13.51%, the control group of 33 patients relapsed, relapse Rate of 52.38%, the difference between the two groups was statistically significant (P <0.05). Conclusion: The combination of heat dampness and dampness method and western medicine in the treatment of ulcerative colitis is effective and stable and durable, which is worth popularizing in clinic.