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目的:分析非接触眼压计测量正常成年人眼压随年龄的变化情况，为眼压的健康宣教提供理论依据。方法:选取2019年6—9月在北京同仁医院进行体检的某单位在职和退休职工，共330名（330眼，右眼）。以年龄每10年分为1组，共7组，其中20～29岁组31名，30～39岁组38名，40～49岁组32名，50～59岁组54名，60～69岁组43名，70～79岁组60名，80～90岁组71名。应用非接触眼压计进行眼压的测量，釆用方差分析比较不同年龄组之间的眼压差异，分析年龄对眼压的影响。结果:本研究中330名受试者年龄20～90岁，眼压值为（13.57±3.42）mmHg。各年龄组眼压值比较差异有统计学意义（n F=4.36，n P<0.01）。将7组重新组合分为20～59岁（155眼）和60～90岁（175眼）两组，其眼压值分别为（14.53±3.18）mmHg和（12.72±3.41）mmHg，两组比较差异有统计学意义（n t=4.98，n P<0.01）。简单线性回归分析显示，随着年龄增加，眼压减少0.04 mmHg/年（95%n CI -0.06～-0.02）。n 结论:在20～90岁正常人中，眼压在60岁之后出现下降。因此，对于眼压正常范围的认定需要根据年龄调整，以促进青光眼早发现、早诊断和早治疗。“,”Objective:To analyze the change of intraocular pressure of normal adults measured by non-contact tonometer with age and to provide theoretical basis for health education of intraocular pressure.Methods:A total of 330 employed workers and retired employees (330 eyes, right eye) from a work unit who underwent physical examination in Beijing Tongren Hospital were selected from June to September 2019. According to the age of each 10 years, they were divided into 7 groups, including 31 cases in 20 to 29 years old group, 38 cases in 30 to 39 years old group, 32 cases in 40 to 49 years old group, 54 cases in 50 to 59 years old group, 43 cases in 60 to 69 years old group, 60 cases in 70 to 79 years old group and 71 cases in 80 to 90 years old group. The intraocular pressure was measured using a non-contact tonometer. Analysis of variance was used to compare the differences in intraocular pressure between different age groups and the effect of age on intraocular pressure was analyzed.Results:The age of the 330 subjects in this study ranged from 20 to 90 years old, and the intraocular pressure value was (13.57±3.42) mmHg. There were statistically significant differences in intraocular pressure among age groups (n F=4.36, n P<0.01) . The 7 groups were regrouped into 20 to 59 years old group (155 eyes) and 60 to 90 years old group (175 eyes) , and intraocular pressure was respectively (14.53±3.18) mmHg and (12.72±3.41) mmHg, and the differences between the two groups were statistically significant (n t=4.98, n P<0.01) . Simple linear regression analysis showed that the intraocular pressure decreased by 0.04 mmHg/year with the increasing age (95%n CI -0.06- -0.02) .n Conclusions:In normal people aged from 20 to 90 years old, the intraocular pressure drops after the age of 60. Therefore, determination of the normal range of intraocular pressure needs to be adjusted according to age so as to promote early detection, early diagnosis and early treatment of glaucoma.