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摘要目的通过体素内不相干运动成像(IVIM)和扩散峰度成像(DKI)来评估鼻腔或鼻窦鳞状细胞癌病人的治疗效果。方法 28例病人分别进行12个b值的单次激发自旋回波EPI序列扫描,计算得到IVIM(灌注分数f、伪扩散系数D*、扩散系数D)、DKI(峰度值K、峰度校正扩散系数DK)和表观扩散系数(ADC)的平均值,第25、50和75百分位数值。分别在治疗前和早期治疗阶段测得各项参数值,并比较治疗前后各参数值变化的百分比。结果多因素逻辑回归分析显示,D(平均值,第25、50和75百分位数值)、K(平均值,第
Abstract Objective To evaluate the therapeutic effect of intranasal or sinus squamous cell carcinoma by means of intra-voxel incoherent motion imaging (IVIM) and diffusion kurtosis imaging (DKI). Methods Twenty-eight patients underwent single-echocardiographic EPI scan of 12 b-values, and IVIM (perfusion score f, pseudo-diffusion coefficient D *, diffusion coefficient D), DKI (kurtosis K, kurtosis correction Diffusion coefficient DK) and apparent diffusion coefficient (ADC), the 25th, 50th and 75th percentile values. The values of each parameter were measured before treatment and in early treatment, and the percentages of changes of each parameter before and after treatment were compared. Results Multivariate logistic regression analysis showed that D (mean, 25th, 50th and 75th percentile values), K (mean,