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探讨乙型肝炎病毒（ＨＢＶ）感染者中丙型肝炎病毒（ＨＣＶ）的感染状况及对肝病的影响。方法对１５０例ＨＢＶ感染者分别用ＥＬＩＳＡ法和ＲＴ－ＰＣＲ法检测抗－ＨＣＶ和ＨＣＶ－ＲＮＡ。结果ＨＢＶ／ＨＣＶ双重感染占１４．６７％；慢性肝炎、肝硬化的双重感染明显高于急性肝炎和病毒携带者；双重感染对ＨＢＶ的复制无明显干扰。结论ＨＢＶ感染者中的ＨＣＶ感染率较高；ＨＣＶ与ＨＢＶ有协同致病作用；ＨＣＶ感染对ＨＢＶ的复制无明显影响；ＨＣＶ与ＨＢＶ主要经血液和血制品传播
To investigate the status of Hepatitis C virus (HCV) infection in hepatitis B virus (HBV) infected patients and its effect on liver diseases. Methods 150 cases of HBV infection were detected by ELISA and RT-PCR anti-HCV and HCV-RNA. Results The double infection rate of HBV / HCV accounted for 14.67%. The double infection rates of chronic hepatitis and cirrhosis were significantly higher than those of acute hepatitis and virus carriers. The double infection had no obvious interference on HBV replication. Conclusions The HCV infection rate in HBV infected persons is high. HCV and HBV have synergistic pathogenicity. HCV infection has no obvious effect on HBV replication. HCV and HBV are mainly transmitted through blood and blood products