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目的评价经皮射频(PRFA)治疗肝脏恶性肿瘤的效果、安全性和价值。方法应用RF-2000射频仪和10电极LeVeen射频针经皮穿刺治疗肝脏恶性肿瘤114例153个病灶,B超引导监测,局麻配合全身镇痛处理,对于肿瘤病灶>2.5 cm者进行分层多点叠合毁损,>5.0 cm或多发者配合肝动脉导管化疗栓塞术,随访观察治疗效果、并发症和生存情况。结果PRFA成功率100%,并发症率6.14%(7/114),无相关死亡。3月、6月、1年、2年、3年生存率分别为100.00%(114/114),97.40%(111/114),74.60%(85/114),59.40%(41/69)和36.80%(7/19)。结论PRFA治疗肝脏恶性肿瘤具有微创、有效、简捷、实用、可重复、相对安全等优势,对各种类型不同大小的肝脏恶性肿瘤均有疗效。
Objective To evaluate the efficacy, safety and value of percutaneous radiofrequency (PRFA) in the treatment of hepatic malignancies. Methods 114 cases of hepatic malignancies were treated with RF-2000 radiofrequency instrument and 10-electrode LeVeen radiofrequency needle percutaneous puncture for 153 lesions. B-ultrasound guided monitoring and local anesthesia combined with systemic analgesia were applied to stratify the tumors more than 2.5 cm Point overlap damage,> 5.0 cm or more with hepatic artery catheter chemoembolization, follow-up observation of the treatment effect, complications and survival. Results The success rate of PRFA was 100% and the complication rate was 6.14% (7/114). There was no related death. The 3-year survival rates were 100.00% (114/114), 97.40% (111/114), 74.60% (85/114) and 59.40% (41/69) in March, June, 36.80% (7/19). Conclusions PRFA has the advantages of minimally invasive, effective, simple, practical, repeatable, and relatively safe for the treatment of hepatic malignancies and is effective in treating various types of liver malignancies of different sizes.