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目的:分析三氯醋酸与胸腺五肽联用治疗宫颈高危型人乳头状瘤病毒(HPV)感染患者的临床疗效。方法:选取2012年6月—2015年6月期间门诊收治的宫颈高危型HPV感染患者100例作为研究对象,采用数字抽取法将其分为观察组和对照组患者,每组50例;对照组患者均给予干扰素栓外用治疗,观察组患者均给予三氯醋酸与胸腺五肽联用治疗,评价两组患者治疗后的总有效率、不良反应的发生率和治疗费用。结果:观察组患者治疗后宫颈高危型HPV感染患者的总有效率为92.00%高于对照组为70.00%(P<0.05);不良反应的发生率为8.00%低于对照组为34.00%(P<0.05);治疗成本费用为(302.33±10.22)元明显优于对照组为(386.26±10.86)元(P<0.05)。结论:三氯醋酸与胸腺五肽联用治疗宫颈高危型HPV感染患者具有显著的临床疗效,可发挥高效的抗病毒作用,安全性高,价格低廉,患者易接受。
Objective: To analyze the clinical efficacy of trichloroacetic acid in combination with thymopentin in the treatment of high-risk cervical papillomavirus (HPV) infection in women. Methods: A total of 100 cases of high risk HPV infection from June 2012 to June 2015 in our hospital were enrolled in this study. Fifty cases in each group were divided into observation group and control group by digital extraction method. Control group Patients were given interferon external suppository therapy, patients in the observation group were given trichloroacetic acid combined with thymopentin treatment, the two groups were evaluated after the total effective rate, the incidence of adverse reactions and treatment costs. Results: The total effective rate of patients with high risk of cervical HPV infection after treatment was 92.00% in the observation group and 70.00% (P <0.05) in the control group. The incidence of adverse reactions was 8.00%, which was lower than 34.00% in the control group (P <0.05). The cost of treatment was (302.33 ± 10.22) yuan better than that of the control group (386.26 ± 10.86) yuan (P <0.05). Conclusion: The combination of trichloroacetic acid and thymopentin in patients with high-risk HPV infection has significant clinical effect, which can exert high antiviral effect. It is safe, inexpensive and easy to be accepted by patients.