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目的:研究静脉注射硫酸镁预防儿童腺样体扁桃体切术后喉痉挛及咳嗽的临床效果.方法:选择2013年11月至2014年9月于我院拟行腺样体扁桃体切除术(ASA Ⅰ～Ⅱ级,3岁＜年龄＜12岁)患儿110例,随机分为研究组和对照组各55例.研究组患儿给予静脉滴注15 mg/kg硫酸镁,对照组患儿给予等量生理盐水.评估患儿的血氧饱和度,并利用四点量表法评估患儿拔除气管内导管后的喉痉挛及咳嗽程度.结果:研究组患儿发生3例(5.5％)轻微喉痉挛和2例(3.6％)中度喉痉挛,对照组患儿发生7例(12.7％)轻微喉痉挛和4例(7.3％)中度喉痉挛,两组比较差异无统计学意义(P＞0.05).两组患儿咳嗽发生率比较差异无统计学意义(P＞0.05).结论:静脉注射硫酸镁15 mg/kg未能有效预防腺样体扁桃体切除术患儿气管拔管后喉痉挛和咳嗽的发生,仅能在一定程度上降低其发生率,提高血氧饱和度.“,”Objective:To study the clinical efficacy of intravenous magnesium sulfate on laryngospasm and coughing after adenotonsillectomy surgery in children.Methods:One hundred and ten children scheduled for adenotonsillectomy surgery (ASA Ⅰ ～ Ⅱ with age 3 to 12 years) from November 2013 to September 2014 in our hospital were chosen in this study,and randomly divided into experiment group and control group with 55 children in each group.Children in experiment group received 15 mg/kg intravenous magnesium sulfate,and control group received normal saline with the same volume.The oxygen saturation,the degree of laryngospasm and coughing after removing the endotracheal tube were assessed with four-point scale.Results:Three cases of children (5.5％) in experiment group with slight laryngospasm and 2 cases (3.6％) with moderate laryngospasm.While 7 cases (12.7％) with slight laryngospasm and 4 cases (7.3 ％) with moderate laryngospasm,there was no significant difference (P＞0.05).Similarly,the incidence of coughing in experiment group was lower than that of control group with no significant difference.Conclusion:Intravenous magnesium sulfate with dose on 15 mg/kg can not prevent laryngospasm and coughing after removing the endotracheal tube in children undergoing adenotonsillectomy,it only can reduce their incidence to a certain extent,but it can make the oxygen saturation to increase.