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目的分析慈溪市受动物伤害人群暴露后处理的状况及其效果,为更好地预防控制狂犬病提供依据。方法在狂犬病门诊收集接受暴露后预防处理人群的基本情况,受伤害的时间、部位、伤害程度、伤人动物的种类、伤口处理、接种人用狂犬病疫苗(Rabies Vacane for Human Use,RabV)的种类,以及人狂犬病免疫球蛋白(Human Ra-bies Immunoglobulin,HRIG)使用等,调查接种RabV后的副反应发生率及其严重程度,以及是否发生人狂犬病。结果慈溪市2007年1~9月共有21 504人接受暴露后的预防处理,95%的人是被犬伤害,62%的人是在遭受动物伤害后12h内接种RabV。所有21 504人全程使用RabV,783人使用HRIG。未发生RabV引起的严重不良反应和人狂犬病病例。结论犬伤仍是当前威胁居民安全诱发狂犬病的主要因素。暴露后能及时正确接受预防处理,使用高效、可靠的RabV和HRIG,能有效预防控制狂犬病。
Objective To analyze the post-exposure condition and its effect in animal-injured people in Cixi City and provide the basis for better prevention and control of rabies. Methods The rabies outpatient department was enrolled in the basic information on the groups receiving prophylaxis and treatment after exposure, the time of injury, the location, the degree of injury, the type of wounding animals, the treatment of wounds, the type of Rabies Vaccine for Human Use (RabV) , And human Ra-bies Immunoglobulin (HRIG) were used to investigate the incidence and severity of side effects following RabV inoculation and the occurrence of human rabies. Results From January to September 2007, a total of 21 504 people in Cixi City received post-exposure prophylaxis. 95% were dog-harmed and 62% were infected with RabV within 12 hours after suffering from animal injuries. All 21 504 people use RabV for the entire journey and 783 people use HRIG. No serious adverse reactions caused by RabV and human rabies cases. Conclusions Canine injury is still the main factor threatening the safety of rabies induced by inhabitants. After exposure to timely and proper treatment of prophylaxis, the use of efficient and reliable RabV and HRIG, can effectively prevent and control rabies.