【摘 要】
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目的：探讨肾癌患者血清 miRNA-378的表达及其临床意义。方法选择明确诊断原发性肾癌患者33例(肾癌组)、肾脏良性肿瘤患者15例(肾良性肿瘤组)以及同期进行健康体检的患者20例(
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目的：探讨肾癌患者血清 miRNA-378的表达及其临床意义。方法选择明确诊断原发性肾癌患者33例(肾癌组)、肾脏良性肿瘤患者15例(肾良性肿瘤组)以及同期进行健康体检的患者20例(健康对照组),采用实时荧光定量反转录聚合酶链反应(RT-qPCR)检测肾癌组术前、术后6个月及另两组血清 miRNA-378的表达水平,并分析 miRNA-378的表达与肾癌临床病理参数的相关性。结果三组血清 miRNA-378表达水平比较差异有统计学意义,肾癌组(术前)、肾脏良性肿瘤组 miRNA-378表达均高于健康对照组,肾癌组(术前)高于肾脏良性肿瘤组,差异均有统计学意义(P
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