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自从六十年代使用麻疹疫苗以来,疫苗接种对象的推荐年龄几经变化。近几年来,普遍实施计划免疫的地区仍有麻疹病例出现,这可能与免疫接种对象的推荐年龄偏大有关。为了解婴儿的被动免疫状态,作者用血凝抑制(HI)试验、酶免疫测定(EIA)和中和试验(NT)检测了2、6和12月龄婴儿的母传抗体水平。于1988年从2、6和12月龄的就诊婴儿中分别收集了64、41和35份血清,其中包括16名婴儿在2和6月龄时先后收集的双份血清。
The recommended ages for vaccination have changed since the measles vaccine was introduced in the 1960s. In recent years, measles cases still occur in areas where universal immunization is planned, which may be related to the age of recommendation of immunized subjects. To understand the infant’s passive immune status, the authors tested maternal antibody levels in infants 2,6 and 12 months of age using the HI test, the EIA and the neutralization test (NT). In 1988, 64, 41 and 35 sera were collected from 2,6 and 12-month-old infants, respectively, including two sera from 16 infants at 2 and 6 months of age.