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结缔组织疾病引起的肾损害肾脏是血液循环丰富的器官,既是全身血管发生非特异性动脉硬化之处,也是因免疫反应而导致特异性血管损伤之处。由于免疫疾病的不同,肾脏各级血管受累的程度亦不同。易伴发肾损害的结缔组织疾病有系统性红斑狼疮、结节性多发性动脉炎、过敏性血管炎、恶性类风湿病、Wegener 肉芽肿、Sch(?)nleia—Henoch 紫癜等;不易伴发肾损害的有进行性全身性硬皮病、Sj(?)gren 综合征;而皮肌类、类风湿性关节炎、混合性结缔组织病、Behcet 病都很少引起肾损害。系统性红斑狼疮产生的肾损害称狼疮性肾炎,女性多见(90%),肾损害的受累率为60～100%,肾功
Kidney damage caused by connective tissue disease The kidneys are organs that are rich in blood circulation, which are both non-specific atherosclerosis of systemic blood vessels and also cause specific vascular damage due to the immune response. Due to the different immune diseases, the degree of vascular involvement at all levels of the kidney is also different. Easily associated with renal damage of connective tissue diseases are systemic lupus erythematosus, polyarteritis nodosa, allergic vasculitis, malignant rheumatoid disease, Wegener granuloma, Sch (?) Nleia-Henoch purpura; not easy to accompany Kidney damage is progressive systemic scleroderma, Sj (?) Gren syndrome; and dermatomyositis, rheumatoid arthritis, mixed connective tissue disease, Behcet disease rarely cause renal damage. Renal damage caused by systemic lupus erythematosus called lupus nephritis, more common in women (90%), the involvement of renal damage rate of 60 to 100%, renal function