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卡介苗接种方法中,以皮内注射法为最好,主要是因为注射剂量准确,阳转率高(95％以上),菌苗剂量小费用经济,免疫力维持时间较长;以上各点已经国内外卡介苗工作者所肯定。但是在新生儿以及一岁以下的幼儿中,用皮内注射法往往发生较多的淋巴结反应,因此新生儿及一岁以下幼儿在选择接种方法上一直存在着问题。以往数年中,上海市对于新生婴儿采用口服法,其优点是阳转率也相当高(历年来约为90％左右),淋巴结反应少(较同年龄内用皮内注射法显见减少)。但是菌苗用量太多,三次口服手续上也较麻烦,特别是家庭接生的婴儿更为不方便,这样就大大地妨碍了大规模推行。为此,上海市结核
BCG vaccination in order to intradermal injection is the best, mainly because of the injection dose is accurate, high positive rate (95% or more), the vaccine dose of tips economy, longer immunity to maintain the above points have been domestic External BCG workers affirmed. However, in neonates and infants under one year of age, intradermal injections usually have more lymph node reactions, so newborns and children under one year of age have been having problems selecting vaccination methods. In the past few years, oral administration of newborn babies in Shanghai has the advantage of a high rate of positive conversion rate (about 90% over the years) and a small number of lymph node reactions (as compared with the decrease in intradermal injection in the same age group). However, the amount of vaccine used too much, three oral procedures are more troublesome, especially for infants born at home more inconvenient, thus greatly hindering the large-scale implementation. To this end, Shanghai tuberculosis