【摘 要】
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目的探讨新辅助化疗在乳腺癌治疗中的价值。方法对甘肃省妇幼保健院收治的经病理活检证实的乳腺癌患者术前给予TEC化疗方案,化疗2周后,评价其疗效。结果新辅助化疗后Ⅱ、Ⅲ期
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目的探讨新辅助化疗在乳腺癌治疗中的价值。方法对甘肃省妇幼保健院收治的经病理活检证实的乳腺癌患者术前给予TEC化疗方案,化疗2周后,评价其疗效。结果新辅助化疗后Ⅱ、Ⅲ期患者缓解总有效率分别为94.4%、80.4%;化疗前后总的保乳率(16%vs61%)比较,差异有统计学意义(P<0.05)。结论新辅助化疗可明显提高可手术乳腺癌患者的保乳率,改善患者的术后生存质量。
Objective To investigate the value of neoadjuvant chemotherapy in the treatment of breast cancer. Methods The chemotherapy regimen of TEC was preoperatively given to patients with breast cancer confirmed by pathological biopsy in Gansu Provincial Maternal and Child Health Care Hospital. After 2 weeks of chemotherapy, the curative effect was evaluated. Results The total effective rates of patients in stage Ⅱ and stage Ⅲ after neoadjuvant chemotherapy were 94.4% and 80.4% respectively. There was significant difference between the two groups (P <0.05). Conclusion Neoadjuvant chemotherapy can significantly improve the rate of breast-conserving in patients with operable breast cancer and improve the postoperative quality of life.
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